Article
Effect of gabapentin-lactam and gamma-aminobutyric acid/lactam analogs on proliferation and phenotype of ovine mesenchymal stem cells.
The International journal of oral & maxillofacial implants - 1 Jan 2000
Sauerbier Sebastian, Gutwald Ralf, Wiedmann-Al-Ahmad Margit, Wolkewitz Martin, Haberstroh Jörg, Obermeyer Julia, Kuenz Arne, Betz Helene, Wolter Franziska, Duttenhoefer Fabian, Schmelzeisen Rainer, Nagursky Heiner, Proksch Susanne, Al-Ahmad Ali
Abstract excerpt
PURPOSE: Classic tissue engineering consists of three components: scaffold, cells, and growth or differentiation factors. Currently, expensive bone morphogenetic proteins are the most common substance used for hard tissue regeneration. An alternative could be gamma-aminobutyric acid/lactam (GABA-lactam) analogs. MATERIALS AND METHODS: The effects of gabapentin-lactam, cis- and trans-8-tertbutyl-GABA-pentinlactam...
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