Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maintaining skeletal muscle mass: lessons learned from hibernation.

Experimental physiology - 1 Apr 2014

Ivakine Evgueni A, Cohn Ronald D

Abstract excerpt

Muscle disuse and starvation are often associated with a catabolic response leading to a dramatic loss of skeletal muscle mass. Hibernating animals represent a unique situation where muscle mass is maintained despite prolonged periods of immobilization and lack of nutrition. We analysed the molecular pathways upregulated during hibernation in an obligate hibernator, the 13-lined ground squirrel (Ictidomys...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Energy Metabolism
Share to Immediate-Early Proteins
Share to Mice, Knockout

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscle, Skeletal

Share to Muscular Atrophy

Share to Organ Size

Share to Protein Serine-Threonine Kinases

Share to Sciuridae

Source

Identifiers

PMID: 24443348
DOI: 10.1113/expphysiol.2013.074344

Genes

SGK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maintaining skeletal muscle mass: lessons learned from hibernation.PMID 24443348Read ↗

Skeletal muscles of hibernating black bears show minimal atrophy and phenotype shifting despite prolonged physical inactivity and starvationSemantic proximity Read ↗

Proteogenomic Analysis of a Hibernating Mammal Indicates Contribution of Skeletal Muscle Physiology to the Hibernation Phenotype.Semantic proximity Read ↗

Deep Sequencing the Transcriptome Reveals Seasonal Adaptive Mechanisms in a Hibernating MammalSemantic proximity Read ↗

Advances in molecular biology of hibernation in mammalsSemantic proximity Read ↗

Mechanisms for maintaining muscleSemantic proximity Read ↗

Skeletal muscle immobilisation-induced atrophy: mechanistic insights from human studiesSemantic proximity Read ↗

Denervation atrophy is independent from Akt and mTOR activation and is not rescued by myostatin inhibition.Semantic proximity Read ↗

The Role of GSK-3β in the Regulation of Protein Turnover, Myosin Phenotype, and Oxidative Capacity in Skeletal Muscle under Disuse Conditions.Semantic proximity Read ↗

Hypothalamic gene expression underlying pre-hibernation satiety.Semantic proximity Read ↗

mTORC1 Promotes Denervation-Induced Muscle Atrophy Through a Mechanism Involving the Activation of FoxO and E3 Ubiquitin LigasesSemantic proximity Read ↗

Reduced ATP turnover during hibernation in relaxed skeletal muscleSemantic proximity Read ↗

Stress-induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle AtrophySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.