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Article

GPI/AMF inhibition blocks the development of the metastatic phenotype of mature multi-cellular tumor spheroids.

Biochimica et biophysica acta - 1 Jun 2014

Gallardo-Pérez Juan Carlos, Rivero-Segura Nadia Alejandra, Marín-Hernández Alvaro, Moreno-Sánchez Rafael, Rodríguez-Enríquez Sara

Abstract excerpt

Epithelial-mesenchymal transition (EMT) and cellular invasiveness are two pivotal processes for the development of metastatic tumor phenotypes. The metastatic profile of non-metastatic MCF-7 cells growing as multi-cellular tumor microspheroids (MCTSs) was analyzed by determining the contents of the EMT, invasive and migratory proteins, as well as their migration and invasiveness potential and capacity to secrete...

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Identifiers

PMID: 24440856
DOI: 10.1016/j.bbamcr.2014.01.013

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GPI
PRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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