Article
GPI/AMF inhibition blocks the development of the metastatic phenotype of mature multi-cellular tumor spheroids.
Biochimica et biophysica acta - 1 Jun 2014
Gallardo-Pérez Juan Carlos, Rivero-Segura Nadia Alejandra, Marín-Hernández Alvaro, Moreno-Sánchez Rafael, Rodríguez-Enríquez Sara
Abstract excerpt
Epithelial-mesenchymal transition (EMT) and cellular invasiveness are two pivotal processes for the development of metastatic tumor phenotypes. The metastatic profile of non-metastatic MCF-7 cells growing as multi-cellular tumor microspheroids (MCTSs) was analyzed by determining the contents of t...
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