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Multistructural biomimetic substrates for controlled cellular differentiation.

Nanotechnology - 14 Feb 2014

Orza Anamaria I, Mihu Carmen, Soritau Olga, Diudea Mircea, Florea Adrian, Matei Horea, Balici Stefana, Mudalige Thilak, Kanarpardy Ganesh K, Biris Alexandru S

Abstract excerpt

Multidimensional scaffolds are considered to be ideal candidates for regenerative medicine and tissue engineering based on their potential to provide an excellent microenvironment and direct the fate of the cultured cells. More recently, the use of stem cells in medicine has opened a new technological opportunity for controlled tissue formation. However, the mechanism through which the substrate directs the...

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PMID: 24434767
DOI: 10.1088/0957-4484/25/6/065102

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