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Dystrophin-deficient cardiomyocytes derived from human urine: New biologic reagents for drug discovery

23 Dec 2013

Abstract excerpt

The ability to extract somatic cells from a patient and reprogram them to pluripotency opens up new possibilities for personalized medicine. Induced pluripotent stem cells (iPSCs) have been employed to generate beating cardiomyocytes from a patient's skin or blood cells. Here, iPSC methods were used to generate cardiomyocytes starting from the urine of a patient with Duchenne muscular dystrophy (DMD). Urine was...

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PMID: 24434629
DOI: 10.1016/j.scr.2013.12.004

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