Article
Development of genetic testing for breast, ovarian and colorectal cancer predisposition: a step closer to targeted cancer prevention.
Current drug targets - 1 Dec 2011
Eccles D M
Abstract excerpt
Individuals who inherit a high penetrance cancer susceptibility gene represent a population in which cancer diagnoses occur at younger ages and much more frequently than in the general population. Screening regimens aimed at early detection of cancer may reduce cancer mortality but in order to reduce cancer incidence, surgery and medical therapies have been advocated. In high genetic risk patients, either...
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