Development of genetic testing for breast, ovarian and colorectal cancer predisposition: a step closer to targeted cancer prevention.

doi:10.2174/138945011798184209

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Article

Development of genetic testing for breast, ovarian and colorectal cancer predisposition: a step closer to targeted cancer prevention.

Current drug targets - 1 Dec 2011

Eccles D M

Abstract excerpt

Individuals who inherit a high penetrance cancer susceptibility gene represent a population in which cancer diagnoses occur at younger ages and much more frequently than in the general population. Screening regimens aimed at early detection of cancer may reduce cancer mortality but in order to reduce cancer incidence, surgery and medical therapies have been advocated. In high genetic risk patients, either...

Topics

Alleles
Animals
Antineoplastic Agents
Breast Neoplasms
Colorectal Neoplasms
Female
General Surgery
Genetic Predisposition to Disease
Genetic Testing
Humans
Ovarian Neoplasms
Penetrance
Risk Assessment
Risk Reduction Behavior
Selective Estrogen Receptor Modulators

Source

Open in PubMed

Identifiers

PMID: 21158705
DOI: 10.2174/138945011798184209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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