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Article

Definition of rapid virologic response with a highly sensitive real-time PCR-based HCV RNA assay in peginterferon alfa-2a plus ribavirin response-guided therapy.

Journal of hepatology - 1 Jun 2010

Sarrazin Christoph, Shiffman Mitchell L, Hadziyannis Stephanos J, Lin Amy, Colucci Giuseppe, Ishida Hiroshi, Zeuzem Stefan

Abstract excerpt

BACKGROUND & AIMS: Assessing hepatitis C virus (HCV)-RNA levels is integral to response-guided therapy. Rules for early discontinuation and determination of treatment duration were mainly established with HCV-RNA assays with a detection limit of 50IU/ml (COBAS Amplicor HCV [CA]). The currently used real-time PCR-based COBAS Ampliprep/COBAS-TaqMan HCV (CAP-CTM) test has a detection limit of approximately 10IU/ml....

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Identifiers

PMID: 20385421
DOI: 10.1016/j.jhep.2010.01.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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