Article
Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility.
BMC veterinary research - 14 Jan 2014
McAloney Camille A, Silverstein Kevin A T, Modiano Jaime F, Bagchi Anindya
Abstract excerpt
BACKGROUND: Enzymatic activity of Telomerase Reverse Transcriptase (TERT) is important in maintaining the telomere length and has been implicated in cancer and aging related pathology. Since cancer susceptibility as well as longevity of dogs vary between breeds, this study involved sequencing the entire TERT gene of Canis familiaris from DNA samples obtained from forty dogs, with ten dogs each of four breeds:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
