Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resveratrol-sulfates provide an intracellular reservoir for generation of parent resveratrol, which induces autophagy in cancer cells

9 Jan 2014

Abstract excerpt

Resveratrol has many proposed health benefits, including the prevention of cancers, but its low bioavailability is considered a limiting factor in translating these effects to humans. Based on in vivo and clinical studies we have shown that resveratrol is indeed rapidly metabolized by phase II enzymes, and that resveratrol sulfates are deconjugated by steroid sulfatases to afford free resveratrol in vitro and in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to RNA Interference and Gene Delivery
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24419144
DOI: 10.4161/auto.27593

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resveratrol-sulfates provide an intracellular reservoir for generation of parent resveratrol, which induces autophagy in cancer cellsPMID 24419144Read ↗

Between the Devil and the Deep Blue Sea—Resveratrol, Sulfotransferases and Sulfatases—A Long and Turbulent Journey from Intestinal Absorption to Target CellsSemantic proximity Read ↗

Resveratrol: A review of preclinical studies for human cancer preventionSemantic proximity Read ↗

The journey of resveratrol from yeast to humanSemantic proximity Read ↗

Resveratrol Targets a Variety of Oncogenic and Oncosuppressive Signaling for Ovarian Cancer Prevention and TreatmentSemantic proximity Read ↗

Resveratrol: From Basic Science to the ClinicSemantic proximity Read ↗

Gut <i>Eggerthella lenta</i> promotes the efficacy of resveratrol through reductive metabolismSemantic proximity Read ↗

Differential Uridyl-diphosphate-Glucuronosyl Transferase 1A enzymatic arsenal explains the specific cytotoxicity of resveratrol towards tumor colorectal cellsSemantic proximity Read ↗

4-Hydroxydibenzyl: a novel metabolite from the human gut microbiota after consuming resveratrolSemantic proximity Read ↗

A novel resveratrol derivative selectively inhibits the proliferation of colorectal cancer cells with KRAS mutation.Semantic proximity Read ↗

Cytotoxic Effect of Resveratrol on Colorectal Cancer Cell LineSemantic proximity Read ↗

Exposure to resveratrol triggers pharmacological correction of fatty acid utilization in human fatty acid oxidation-deficient fibroblasts.Semantic proximity Read ↗

Conjugated Physiological Resveratrol Metabolites Induce Senescence in Breast Cancer Cells: Role of p53/p21 and p16/Rb Pathways, and ABC TransportersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.