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Article

Correcting the cystic fibrosis disease mutant, A455E CFTR.

PloS one - 1 Jan 2014

Cebotaru Liudmila, Rapino Daniele, Cebotaru Valeriu, Guggino William B

Abstract excerpt

Cystic fibrosis is caused by more than 1000 mutations, the most common being the ΔF508 mutation. These mutations have been divided into five classes [1], with ΔF508 CFTR in class II. Here we have studied the class V mutation A455E. We report that the mature and immature bands of A455E are rapidly...

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Source

Open in PubMed Open full text

Identifiers

PMID: 24416359
DOI: 10.1371/journal.pone.0085183
PMCID: PMC3885674

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24416359-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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