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Article

Evolutionary changes in gene expression, coding sequence and copy-number at the Cyp6g1 locus contribute to resistance to multiple insecticides in Drosophila.

PloS one - 1 Jan 2014

Harrop Thomas W R, Sztal Tamar, Lumb Christopher, Good Robert T, Daborn Phillip J, Batterham Philip, Chung Henry

Abstract excerpt

Widespread use of insecticides has led to insecticide resistance in many populations of insects. In some populations, resistance has evolved to multiple pesticides. In Drosophila melanogaster, resistance to multiple classes of insecticide is due to the overexpression of a single cytochrome P450 gene, Cyp6g1. Overexpression of Cyp6g1 appears to have evolved in parallel in Drosophila simulans, a sibling species of...

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Identifiers

PMID: 24416303
DOI: 10.1371/journal.pone.0084879
PMCID: PMC3885650

Genes

DDT

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Source receipt: pubmed, retrieved 7 Sept 2026.

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