Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ALK gene copy number gain and its clinical significance in hepatocellular carcinoma.

World journal of gastroenterology - 7 Jan 2014

Jia Shou-Wei, Fu Sha, Wang Fang, Shao Qiong, Huang Hong-Bing, Shao Jian-Yong

Abstract excerpt

AIM: To examine the status and clinical significance of anaplastic lymphoma kinase (ALK) gene alterations in hepatocellular carcinoma (HCC) patients. METHODS: A total of 213 cases of HCC were examined by fluorescent in situ hybridization using dual color break-apart ALK probes for the detection of chromosomal translocation and gene copy number gain. HCC tissue microarrays were constructed, and the correlation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaplastic Lymphoma Kinase
Share to Chi-Square Distribution

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Kaplan-Meier Estimate

Share to Neoplasm Grading

Share to Proportional Hazards Models

Share to Receptor Protein-Tyrosine Kinases

Share to Tissue Array Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 24415871
DOI: 10.3748/wjg.v20.i1.183
PMCID: PMC3886007

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ALK gene copy number gain and its clinical significance in hepatocellular carcinoma.PMID 24415871Read ↗

ALK gene copy number gains in non-small-cell lung cancer: prognostic impact and clinico-pathological correlations.Semantic proximity Read ↗

ALK gene amplification is associated with poor prognosis in colorectal carcinomaSemantic proximity Read ↗

Genomic Landscape of Copy Number Aberrations Enables the Identification of Oncogenic Drivers in Hepatocellular CarcinomaSemantic proximity Read ↗

Correlating genomic copy number alterations with clinicopathologic findings in a case series of hepatocellular carcinomaSemantic proximity Read ↗

A new look at the ALK gene in cancer: copy number gain and amplificationSemantic proximity Read ↗

ALK protein expression and gene copy number alterations in triple-negative breast cancer: Clinical implications.Semantic proximity Read ↗

Prediction of early-stage hepatocellular carcinoma using OncoScan chromosomal copy number aberration dataSemantic proximity Read ↗

Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinomaSemantic proximity Read ↗

Prognostic significance of <i>c‐myc</i> and <i>AIB1</i> amplification in hepatocellular carcinomaSemantic proximity Read ↗

PCNA-associated factor (KIAA0101/PCLAF) overexpression and gene copy number alterations in hepatocellular carcinoma tissuesSemantic proximity Read ↗

Co-existence of positive MET FISH status with EGFR mutations signifies poor prognosis in lung adenocarcinoma patients.Semantic proximity Read ↗

Native and rearranged ALK copy number and rearranged cell count in non–small cell lung cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.