Article
Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: A case-control study and a computational analysis.
Irish journal of medical science - 1 Nov 2017
Mazaheri M, Karimian M, Behjati M, Raygan F, Hosseinzadeh Colagar A
Abstract excerpt
BACKGROUND: The p22phox gene encodes the main subunit of NADH/NADPH-oxidase. This enzyme is expressed in smooth muscle cells of arteries, and it produces the reactive oxygen species. On the other hand, oxidative stress plays a main role in the pathogenesis of coronary artery disease (CAD). AIM: The aim of this study is to evaluate the association between rs4673 and rs1049255 polymorphisms of p22phox gene with CAD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
