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Article

<b>Chronic Arsenic Exposure and Angiogenesis in Human Bronchial Epithelial Cells via the ROS/miR-199a-5p/HIF-1</b> α <b>/COX-2 Pathway</b>

10 Jan 2014

Abstract excerpt

BACKGROUND: Environmental and occupational exposure to arsenic is a major public health concern. Although it has been identified as a human carcinogen, the molecular mechanism underlying the arsenic-induced carcinogenesis is not well understood. OBJECTIVES: We aimed to determine the role and mechanisms of miRNAs in arsenic-induced tumor angiogenesis and tumor growth. METHODS: We utilized an in vitro model in...

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PMID: 24413338
DOI: 10.1289/ehp.1307545

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