Article
Functional characterization of a veA-dependent polyketide synthase gene in Aspergillus flavus necessary for the synthesis of asparasone, a sclerotium-specific pigment.
Fungal genetics and biology : FG & B - 1 Mar 2014
Cary Jeffrey W, Harris-Coward Pamela Y, Ehrlich Kenneth C, Di Mavungu José Diana, Malysheva Svetlana V, De Saeger Sarah, Dowd Patrick F, Shantappa Sourabha, Martens Stacey L, Calvo Ana M
Abstract excerpt
The filamentous fungus, Aspergillus flavus, produces the toxic and carcinogenic, polyketide synthase (PKS)-derived family of secondary metabolites termed aflatoxins. While analysis of the A. flavus genome has identified many other PKSs capable of producing secondary metabolites, to date, only a few other metabolites have been identified. In the process of studying how the developmental regulator, VeA, affects A....
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