Article
[Association of TNF-1031T/C and clinical efficacy of insulin therapy in newly diagnosed type 2 diabetics].
Zhonghua yi xue za zhi - 29 Oct 2013
Xu Hai-xia, Xu Wen, Xu Fen, Liang Hua, Yan Jin-hua, Chen Zhi-peng, Sun Yi-ting, Yao Bin, Weng Jian-ping
Abstract excerpt
OBJECTIVE: Tumor necrosis factor (TNF ) locus has been a long-standing type 2 diabetes (T2D) candidate gene. Few studies have been conducted on TNF SNP (single nucleotide polymorphism) as rs1799964 (T-1031C), rs1800630 (A-863C) and rs1799724 (C-857T) in T2D. The purpose of this study is to examine the association of TNF SNP and T2D in a case control study and further explore whether these SNPs influence the...
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