Article
Characterization of pulmonary cysts in Birt-Hogg-Dubé syndrome: histopathological and morphometric analysis of 229 pulmonary cysts from 50 unrelated patients.
Histopathology - 1 Jul 2014
Kumasaka Toshio, Hayashi Takuo, Mitani Keiko, Kataoka Hideyuki, Kikkawa Mika, Tobino Kazunori, Kobayashi Etsuko, Gunji Yoko, Kunogi Makiko, Kurihara Masatoshi, Seyama Kuniaki
Abstract excerpt
AIMS: To characterize the pathological features of pulmonary cysts, and to elucidate the possible mechanism of cyst formation in the lungs of patients with Birt-Hogg-Dubé syndrome (BHDS), a tumour suppressor gene syndrome, using histological and morphometric analyses. METHODS AND RESULTS: We evaluated 229 lung cysts from 50 patients with BHDS and 117 from 34 patients with primary spontaneous pneumothorax (PSP)...
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