Article
Automatic context-specific subnetwork discovery from large interaction networks.
PloS one - 1 Jan 2014
Saha Ashis, Tan Aik Choon, Kang Jaewoo
Abstract excerpt
Genes act in concert via specific networks to drive various biological processes, including progression of diseases such as cancer. Under different phenotypes, different subsets of the gene members of a network participate in a biological process. Single gene analyses are less effective in identifying such core gene members (subnetworks) within a gene set/network, as compared to gene set/network-based analyses....
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