Article
Prognostic and predictive biomarkers: tools in personalized oncology.
Molecular diagnosis & therapy - 1 Jun 2014
Nalejska Ewelina, Mączyńska Ewa, Lewandowska Marzena Anna
Abstract excerpt
Oncology indispensably leads us to personalized medicine, which allows an individual approach to be taken with each patient. Personalized oncology is based on pharmacogenomics and the effect of genetic differences in individuals (germline and somatic) on the way cancer patients respond to chemotherapeutics. Biomarkers detected using molecular biology tools allow the molecular characterization of cancer signatures...
Topics
- Biomarkers, Tumor
- DNA Methylation
- Humans
- MicroRNAs
- Molecular Targeted Therapy
- Mutation
- Neoplasms
- Neoplastic Cells, Circulating
- Pathology, Molecular
- Polymorphism, Single Nucleotide
- Precision Medicine
