Article
Systemic therapeutic strategies for GEP-NETS: what can we expect in the future?
Cancer metastasis reviews - 1 Mar 2014
Raymond E, García-Carbonero R, Wiedenmann B, Grande E, Pavel M
Abstract excerpt
Over the last few years, there have been important advances in the understanding of the molecular biology of neuroendocrine tumors (NETs) that have already translated into relevant advances in the clinic. Several studies have extensively assessed the mutational profile of NETs, and have shown the key roles that angiogenesis and the PI3K-AKT-mTOR pathway play in the pathogenesis of these tumors. Recent data has...
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