Article
Molecular pathogenesis of neuroendocrine tumors: implications for current and future therapeutic approaches.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2013
Oberg Kjell, Casanovas Oriol, Castaño Justo P, Chung Daniel, Delle Fave Gianfranco, Denèfle Patrice, Harris Philip, Khan Mohid S, Kulke Matthew H, Scarpa Aldo, Tang Laura H, Wiedenmann Bertram
Abstract excerpt
The treatment landscape and biologic understanding of neuroendocrine tumors (NET) has shifted dramatically in recent years. Recent studies have shown that somatostatin analogues have the potential not only to control symptoms of hormone hypersecretion but also have the ability to slow tumor growth in patients with advanced carcinoid. The results of clinical trials have further shown that the VEGF pathway...
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