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Article

Influence of endothelial nitric oxide synthase gene polymorphisms (-786T/C, 4a4b, 894G/T) on Iranian kidney transplant recipients.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 Feb 2013

Azarpira Negar, Aghdai Mahdokht H, Geramizadeh Bita, Bahador Ali, Ayatolahi Maryam, Darai Masumeh

Abstract excerpt

OBJECTIVES: Nitric oxide is a major mediator in vascular biology and regulator of regional blood flow. Its production is catalyzed by the enzyme endothelial nitric oxide synthase. Protective actions of nitric oxide in ischemia and reperfusion are due to its potential as an antioxidant and anti-inflammatory agent, along with its inhibitory effects on cell signaling pathways of nuclear proteins, such as NF-kB. The...

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PMID: 23387538
DOI: 10.6002/ect.2012.0040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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