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Article

Investigation of 305 patients with myelodysplastic syndromes and 20q deletion for associated cytogenetic and molecular genetic lesions and their prognostic impact.

British journal of haematology - 1 Mar 2014

Bacher Ulrike, Haferlach Torsten, Schnittger Susanne, Zenger Melanie, Meggendorfer Manja, Jeromin Sabine, Roller Andreas, Grossmann Vera, Krauth Maria-Theresa, Alpermann Tamara, Kern Wolfgang, Haferlach Claudia

Abstract excerpt

In patients with myelodysplastic syndromes (MDS), sole 20q deletion [del(20q)] is a recurrent favourable abnormality. We studied additional molecular and cytogenetic lesions and their prognostic impact in 305 MDS patients with del(20q) (229 males/76 females; 29-90 years). All patients were investigated by cytomorphology and chromosome banding analysis (CBA), subsets by fluorescence in situ hybridization,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24372512
DOI: 10.1111/bjh.12710

Genes

EYA2
PTPRT
SRSF2

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