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Article

Serum osteopontin, but not OPN gene polymorphism, is associated with LVH in essential hypertensive patients.

Journal of molecular medicine (Berlin, Germany) - 1 May 2014

Hou Xuwei, Hu Zhaohui, Huang Xiaohua, Chen Yan, He Xiuying, Xu Haiying, Wang Ningfu

Abstract excerpt

UNLABELLED: This study aims to investigate the role of osteopontin (OPN) genetic polymorphisms in the occurrence of left ventricular hypertrophy (LVH) in Chinese patients with essential hypertension (EH). A total of 1,092 patients diagnosed with EH were recruited. Three single nucleotide polymorphisms (SNP) on the promoter region of the OPN gene, including -66T/G, -156G/GG, and -443C/T were genotyped. The serum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24370940
DOI: 10.1007/s00109-013-1099-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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