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Article

Pathogenetic role of Factor VII deficiency and thrombosis in cross-reactive material positive patients.

Laboratory hematology : official publication of the International Society for Laboratory Hematology - 1 Dec 2013

Girolami A, Sambado L, Bonamigo E, Ferrari S, Lombardi A M

Abstract excerpt

Congenital Factor VII (FVII) deficiency can be divided into two groups: cases of "true" deficiency, or cross-reactive material (CRM) negative and variants that are cross-reactive material positive.The first form is commonly recognized as Type I condition whereas the second one is known as Type II. FVII deficiency has been occasionally associated with thrombotic events, mainly venous. The reasons underlying this...

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PMID: 24370871
DOI: 10.1532/LH96.12011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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