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Constructing and characterizing a bioactive small molecule and microRNA association network for Alzheimer's disease

18 Dec 2013

Abstract excerpt

Alzheimer's disease (AD) is an incurable neurodegenerative disorder. Much effort has been devoted to developing effective therapeutic agents. Recently, targeting microRNAs (miRNAs) with small molecules has become a novel therapy for human diseases. In this study, we present a systematic computational approach to construct a bioactive Small molecule and miRNA association Network in AD (SmiRN-AD), which is based on...

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PMID: 24352679
DOI: 10.1098/rsif.2013.1057

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