Article
Variational attenuation correction in two-view confocal microscopy.
BMC bioinformatics - 18 Dec 2013
Schmidt Thorsten, Dürr Jasmin, Keuper Margret, Blein Thomas, Palme Klaus, Ronneberger Olaf
Abstract excerpt
BACKGROUND: Absorption and refraction induced signal attenuation can seriously hinder the extraction of quantitative information from confocal microscopic data. This signal attenuation can be estimated and corrected by algorithms that use physical image formation models. Especially in thick heterogeneous samples, current single view based models are unable to solve the underdetermined problem of estimating the...
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