Non‐invasive prenatal testing for fetal chromosomal abnormalities by low‐coverage whole‐genome sequencing of maternal plasma <scp>DNA</scp> : review of 1982 consecutive cases in a single center

Abstract excerpt

OBJECTIVE: To review the performance of non-invasive prenatal testing (NIPT) by low-coverage whole-genome sequencing of maternal plasma DNA at a single center. METHODS: The NIPT result and pregnancy outcome of 1982 consecutive cases were reviewed. NIPT was based on low coverage (0.1×) whole-genome sequencing of maternal plasma DNA. All subjects were contacted for pregnancy and fetal outcome. RESULTS: Of the 1982...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer Genomics and Diagnostics
• Share to Genomic variations and chromosomal abnormalities