Article
Screening of genes related with intervertebral disc disease by dynamic differential interaction network analysis.
European review for medical and pharmacological sciences - 1 Dec 2013
Jiang K, Li Y, Cao G-Y, Liu D, Liao D-F, Gong K, Xie Q-Y, Ma Z-H, Pan X-M
Abstract excerpt
AIM: Gene expression profiles for intervertebral disc (IVD) cells treated with different osmolarities were compared to identify key genes associated with intervertebral disc diseases. MATERIALS AND METHODS: Microarray data was downloaded from Gene Expression Omnibus (GEO) database and pre-processed using package of R. Gene co-expression was determined with Pearson correlation coefficient. Interaction networks...
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