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Article

Role of IL-6 in Mycobacterium avium–Associated Immune Reconstitution Inflammatory Syndrome

12 Dec 2013

Abstract excerpt

Immune reconstitution inflammatory syndrome (IRIS) is a major adverse event of antiretroviral therapy in HIV infection, and paradoxically occurs as HIV viremia is suppressed and CD4 T cell numbers recover. IRIS reflects pathogenic immune responses against opportunistic infections acquired during the period of immunodeficiency, but little is understood about the mechanisms of inflammatory pathology. In this study,...

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PMID: 24337386
DOI: 10.4049/jimmunol.1301004

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