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A Recessive oca2 Mutation Underlies Albinism in Xiphophorus Fish.

Pigment cell & melanoma research - 1 Jul 2026

Xing Yanting, Boswell William, Parker Jessica, Du Kang, Schartl Manfred, Lu Yuan

Abstract excerpt

Oculocutaneous albinism (OCA) is a group of genetic disorders characterized by impaired melanin production, leading to reduced pigmentation in the skin, hair, and eyes. Xiphophorus, a genus of small freshwater fish, has been a pivotal model organism in pigmentation disorder research, providing key findings in the genetic pathways governing physiological and pathological pigment cell biology. Leveraging the...

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Identifiers

PMID: 42487449
DOI: 10.1111/pcmr.70113
PMCID: PMC13392481

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