Article
Short duration of lamivudine for the prevention of hepatitis B virus transmission in pregnancy: lack of potency and selection of resistance mutations.
Journal of viral hepatitis - 1 Nov 2014
Ayres A, Yuen L, Jackson K M, Manoharan S, Glass A, Maley M, Yoo W, Hong S P, Kim S-O, Luciani F, Bowden D S, Bayliss J, Levy M T, Locarnini S A
Abstract excerpt
This study sought to assess the antiviral efficacy of lamivudine (LMV) administered during third trimester to reduce maternal viraemia and to identify the emergence of LMV resistance. A prospective observational analysis was performed on 26 mothers with high viral load (>10⁷ IU/mL). Twenty-one wo...
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