Article
Vitamin D status in Hashimoto's thyroiditis and its association with vitamin D receptor genetic variants.
The Journal of steroid biochemistry and molecular biology - 1 Sept 2021
Hanna Hany William Z, Rizzo Cristiano, Abdel Halim Radwa Marawan, El Haddad Hemmat Elewa, Salam Randa, El-Sayed Abou-Youssef Hazem
Abstract excerpt
BACKGROUND: Hashimoto's thyroiditis (HT) is considered the predominant cause of hypothyroidism in iodine sufficient countries. The deficiency of 25-OH-vitamin D3 serum level and the variation of vitamin D receptor (VDR) gene were implicated in a number of autoimmune disorders. This study aimed to test the hypothesis linking between VDR FokI and BsmI variants and HT, in addition to explain their impact on...
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