Article
Dynamics of the pneumococcal population causing acute exacerbations in COPD patients in a Barcelona hospital (2009-12): comparison with 2001-04 and 2005-08 periods.
The Journal of antimicrobial chemotherapy - 1 Apr 2014
Domenech Arnau, Ardanuy Carmen, Tercero Anais, García-Somoza Dolors, Santos Salud, Liñares Josefina
Abstract excerpt
BACKGROUND: Pneumococci are an important cause of acute exacerbations in patients with chronic obstructive pulmonary disease (COPD). In the last decade, the pneumococcal population has changed, mainly due to the introduction of the 7-valent conjugate vaccine (PCV7). METHODS: We analysed the antimicrobial susceptibility (microdilution), serotype (PCR) and genotype (PFGE/multilocus sequence typing) of pneumococci...
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