Using systems approaches to address challenges for clinical implementation of pharmacogenomics.

Abstract excerpt

Many genetic variants have been shown to affect drug response through changes in drug efficacy and likelihood of adverse effects. Much of pharmacogenomic science has focused on discovering and clinically implementing single gene variants with large effect sizes. Given the increasing complexities of drug responses and their variability, a systems approach may be enabling for discovery of new biology in this area....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genotype
• Share to Models, Biological