Article
Integrative systems biology approaches in asthma pharmacogenomics.
Pharmacogenomics - 1 Sept 2012
Dahlin Amber, Tantisira Kelan G
Abstract excerpt
In order to improve therapeutic outcomes, there is a tremendous need to identify patients who are likely to respond to a given asthma treatment. Pharmacogenomic studies have explained a portion of the variability in drug response and provided an increasing list of candidate genes and SNPs. However, as phenotypic variation arises from a network of complex interactions among genetic and environmental factors,...
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