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Article

Prediction of gene phenotypes based on GO and KEGG pathway enrichment scores.

BioMed research international - 1 Jan 2013

Zhang Tao, Jiang Min, Chen Lei, Niu Bing, Cai Yudong

Abstract excerpt

Observing what phenotype the overexpression or knockdown of gene can cause is the basic method of investigating gene functions. Many advanced biotechnologies, such as RNAi, were developed to study the gene phenotype. But there are still many limitations. Besides the time and cost, the knockdown of some gene may be lethal which makes the observation of other phenotypes impossible. Due to ethical and technological...

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Identifiers

PMID: 24312912
DOI: 10.1155/2013/870795
PMCID: PMC3838811

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