Article
No evidence of association between common autoimmunity STAT4 and IL23R risk polymorphisms and non-anterior uveitis.
PloS one - 1 Jan 2013
Cénit María Carmen, Márquez Ana, Cordero-Coma Miguel, Gorroño-Echebarría Marina Begoña, Fonollosa Alejandro, Adán Alfredo, Martínez-Berriotxoa Agustín, Díaz Valle David, Pato Esperanza, Blanco Ricardo, Cañal Joaquín, Díaz-Llopis Manuel, García Serrano José Luis, de Ramón Enrique, Del Rio María José, Martín-Villa José Manuel, Molins Blanca, Ortego-Centeno Norberto, Martín Javier
Abstract excerpt
OBJECTIVE: STAT4 and IL23R loci represent common susceptibility genetic factors in autoimmunity. We decided to investigate for the first time the possible role of different STAT4/IL23R autoimmune disease-associated polymorphisms on the susceptibility to develop non-anterior uveitis and its main clinical phenotypes. METHODS: Four functional polymorphisms (rs3821236, rs7574865, rs7574070, and rs897200) located...
