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Article

High-throughput microRNA profiling of pediatric high-grade gliomas

4 Dec 2013

Abstract excerpt

BACKGROUND: High-grade gliomas (HGGs) account for 15% of all pediatric brain tumors and are a leading cause of cancer-related mortality and morbidity. Pediatric HGGs (pHGGs) are histologically indistinguishable from their counterpart in adulthood. However, recent investigations indicate that differences occur at the molecular level, thus suggesting that the molecular path to gliomagenesis in childhood is distinct...

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PMID: 24305714
DOI: 10.1093/neuonc/not215

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