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Article

microRNA Profiling Identifies Cancer-Specific and Prognostic Signatures in Pediatric Malignancies

26 Aug 2009

Abstract excerpt

PURPOSE: microRNAs have been shown to be involved in different human cancers. We therefore have performed expression profiles on a panel of pediatric tumors to identify cancer-specific microRNAs. We also investigated if microRNAs are coregulated with their host gene. EXPERIMENTAL DESIGN: We performed parallel microRNAs and mRNA expression profiling on 57 tumor xenografts and cell lines representing 10 different...

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PMID: 19706822
DOI: 10.1158/1078-0432.ccr-08-3287

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