Article
Low-density plating is sufficient to induce cardiac hypertrophy and electrical remodeling in highly purified human iPS cell-derived cardiomyocytes.
Journal of pharmacological and toxicological methods - 1 Jan 2000
Uesugi Mai, Ojima Atsuko, Taniguchi Tomohiko, Miyamoto Norimasa, Sawada Kohei
Abstract excerpt
INTRODUCTION: Cardiac hypertrophy is a leading cause of many cardiovascular diseases, including heart failure, but its pathological mechanism is not fully understood. This study used highly purified human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes to produce an in vitro hypertro...
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