Article
Role of interleukin-28B polymorphism as a predictor of sustained virological response in patients with chronic hepatitis C treated with triple therapy: a systematic review and meta-analysis.
Clinical drug investigation - 1 May 2013
Bota Simona, Sporea Ioan, Şirli Roxana, Neghină Adriana Maria, Popescu Alina, Străin Mihnea
Abstract excerpt
BACKGROUND AND OBJECTIVE: Chronic hepatitis C represents an important health problem. The aim of our meta-analysis was to establish the role of reference single nucleotide (rs) 12979860 allele of interleukin-28B (IL28B) CC versus CT+TT genotype (the most researched allele of IL28B) as a predictor of sustained virological response (SVR) in patients with chronic hepatitis C treated with triple therapy. METHODS: The...
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