Article
The ZC3HC1 rs11556924 polymorphism is associated with increased carotid intima-media thickness in patients with rheumatoid arthritis.
Arthritis research & therapy - 11 Oct 2013
López-Mejías Raquel, Genre Fernanda, García-Bermúdez Mercedes, Corrales Alfonso, González-Juanatey Carlos, Llorca Javier, Miranda-Filloy José A, Rueda-Gotor Javier, Blanco Ricardo, Castañeda Santos, Martín Javier, González-Gay Miguel A
Abstract excerpt
INTRODUCTION: Rheumatoid arthritis (RA) is a complex polygenic disease associated with chronic inflammation, accelerated atherosclerosis and increased cardiovascular (CV) mortality. A recent meta-analysis has described the ZC3HC1 rs11556924 polymorphism as one of the most important signals associated with coronary artery disease (CAD) in non-rheumatic Caucasian individuals. In this study we evaluated the...
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