Decreased apopto-phagocytic gene expression in the macrophages of systemic lupus erythematosus patients

Abstract excerpt

The clearance of apoptotic cells has an important role in the maintenance of tissue homeostasis and in the protection of tissues from the inflammatory and immunogenic contents of dying cells. A defect in the recognition and phagocytosis of apoptotic cells contributes to the development of chronic inflammation and autoimmune disorders. We have observed that compared with healthy donors, differentiated macrophages...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Immune cells in cancer
• Share to Phagocytosis and Immune Regulation
• Share to Systemic Lupus Erythematosus Research