Article
Estimating the size and number of autophagic bodies by electron microscopy.
Autophagy - 1 Jan 2014
Backues Steven K, Chen Dachuan, Ruan Jishou, Xie Zhiping, Klionsky Daniel J
Abstract excerpt
Much recent and ongoing research is focused on understanding the mechanisms and regulation of autophagy, a cellular self-degradation pathway with many links to human health. Although many assays exist to measure the total magnitude of autophagy, electron microscopy remains the tool of choice for the determination of the size and the number of autophagosomes formed in a given mutant or under given induction...
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