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Rapid Electrokinetic Isolation of Cancer-Related Circulating Cell-Free DNA Directly from Blood

23 Nov 2013

Abstract excerpt

BACKGROUND: Circulating cell-free DNA (ccf-DNA) is becoming an important biomarker for cancer diagnostics and therapy monitoring. The isolation of ccf-DNA from plasma as a "liquid biopsy" may begin to replace more invasive tissue biopsies for the detection and analysis of cancer-related mutations. Conventional methods for the isolation of ccf-DNA from plasma are costly, time-consuming, and complex, preventing the...

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Identifiers

PMID: 24270796
DOI: 10.1373/clinchem.2013.214874

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