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Article

Antihistamine-resistant angioedema in women with negative family history: estrogens and F12 gene mutations.

The American journal of medicine - 1 Dec 2013

Bork Konrad, Wulff Karin, Witzke Günther, Stanger Christian, Lohse Peter, Hardt Jochen

Abstract excerpt

BACKGROUND: In women with sporadic recurrent angioedema with an unknown cause who are unresponsive to antihistamines and have normal C1 inhibitor activity and a negative family history of angioedema, it is unclear whether they have idiopathic angioedema or hereditary angioedema with normal C1 inhibitor, and what impact exogenous estrogens have on their angioedema. METHODS: A cohort of 147 women was analyzed for...

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Identifiers

PMID: 24262729
DOI: 10.1016/j.amjmed.2013.05.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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