Article
Memory and modularity in cell-fate decision making.
Nature - 28 Nov 2013
Norman Thomas M, Lord Nathan D, Paulsson Johan, Losick Richard
Abstract excerpt
Genetically identical cells sharing an environment can display markedly different phenotypes. It is often unclear how much of this variation derives from chance, external signals, or attempts by individual cells to exert autonomous phenotypic programs. By observing thousands of cells for hundreds of consecutive generations under constant conditions, we dissect the stochastic decision between a solitary, motile...
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