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Article

The prion hypothesis in Parkinson's disease: Braak to the future

8 May 2013

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative disorder typified by the presence of intraneuronal inclusions containing aggregated alpha synuclein (αsyn). The progression of parkinsonian pathology and clinical phenotype has been broadly demonstrated to follow a specific pattern, most notably described by Braak and colleagues. In more recent times it has been hypothesized that αsyn itself may be a...

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PMID: 24252164
DOI: 10.1186/2051-5960-1-2

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