Article
Association weight matrix for the genetic dissection of puberty in beef cattle.
Proceedings of the National Academy of Sciences of the United States of America - 3 Aug 2010
Fortes Marina R S, Reverter Antonio, Zhang Yuandan, Collis Eliza, Nagaraj Shivashankar H, Jonsson Nick N, Prayaga Kishore C, Barris Wes, Hawken Rachel J
Abstract excerpt
We describe a systems biology approach for the genetic dissection of complex traits based on applying gene network theory to the results from genome-wide associations. The associations of single-nucleotide polymorphisms (SNP) that were individually associated with a primary phenotype of interest, age at puberty in our study, were explored across 22 related traits. Genomic regions were surveyed for genes harboring...
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